SCHEMBL251880

SCHEMBL251880

CCCCCOP(=O)(Cl)Cl

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 9/20 0.58
LPAR2 Q9HBW0 7/20 0.58
LPAR1 Q92633 4/20 0.58
CYP3A4 P08684 2/20 0.54
TP53 P04637 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
LMNA P02545 1/20 0.46
ESR1 P03372 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CDC25A P30304 1/20 0.46
AGTR1 P30556 1/20 0.46
AKT1 P31749 1/20 0.46
ADRA1A P35348 1/20 0.46
KCNH2 Q12809 1/20 0.46
TSHR P16473 1/20 0.41
LPAR5 Q9H1C0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29151408 0.98 LPAR3 (0.61) LPAR3LPAR2LPAR1CYP3A4TP53
SCHEMBL11290063 0.98 LPAR3 (0.61) LPAR3LPAR2LPAR1CYP3A4TP53
SCHEMBL6263500 0.98 LPAR3 (0.61) LPAR3LPAR2LPAR1CYP3A4TP53
SCHEMBL11289118 0.98 LPAR3 (0.61) LPAR3LPAR2LPAR1CYP3A4TP53
SCHEMBL3129987 0.98 LPAR3 (0.61) LPAR3LPAR2LPAR1CYP3A4TP53
SCHEMBL25170776 0.98 LPAR3 (0.61) LPAR3LPAR2LPAR1CYP3A4TP53
SCHEMBL1261030 0.98 LPAR3 (0.61) LPAR3LPAR2LPAR1CYP3A4TP53
SCHEMBL7550122 0.98 LPAR3 (0.61) LPAR3LPAR2LPAR1CYP3A4TP53
SCHEMBL11292235 0.98 LPAR3 (0.61) LPAR3LPAR2LPAR1CYP3A4TP53
SCHEMBL27938963 0.98 LPAR3 (0.56) LPAR3LPAR2LPAR1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116196868-A Continuous production device and continuous preparation method of diaryl chlorophosphate 浙江万盛股份有限公司 2023-06-02 CN claimed
US-8350074-B2 Low triphenylphosphate, high phosphorous content isopropyl phenyl phosphates with high ortho alkylation ALBEMARLE CORPORATION (US) 2013-01-08 US claimed
US-20120004438-A1 Low Triphenylphosphate, High Phosphorous Content Isopropyl Phenyl Phosphates With High Ortho Alkylation ALBEMARLE CORPORATION (US) 2012-01-05 US claimed
US-20100012906-A1 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION ALBEMARLE CORPORATION (US) 2010-01-21 US claimed
JP-2009534469-A 2009-09-24 JP claimed
EP-2021347-A2 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION Albermarle Corporation (US) 2009-02-11 EP claimed
WO-2007127691-A2 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION ALBERMARLE CORPORATION (US) 2007-11-08 WO claimed
US-6455665-B1 ETHYL OR HEXYL DICHLOROPHOSPHATE OR DICHLOROPHOSPHONATE REACTED WITH A POLYESTER PREPOLYMER GUILFORD PHARMACEUTICALS INC. 2002-09-24 US claimed
US-20020028911-A1 Ethyl or hexyl dichlorophosphate or dichlorophosphonate reacted with a polyester prepolymer EISAI INC. 2002-03-07 US claimed
WO-2002004544-A2 POLYMERS AND POLYMERIZATION PROCESSES GUILFORD PHARMACEUTICALS (US) 2002-01-17 WO claimed
US-4144290-A Production of bromoaryl chlorophosphates BAYER AKTIENGESELLSCHAFT (DE) 1979-03-13 US claimed
EP-4730479-A2 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME Kyoto University (JP) 2026-04-22 EP disclosed
US-12476242-B2 Lithium secondary battery SK ON CO., LTD. (KR) 2025-11-18 US disclosed
US-20250246685-A1 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME KYOTO UNIVERSITY (JP) 2025-07-31 US disclosed
EP-4428982-A1 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME Kyoto University (JP) 2024-09-11 EP disclosed
US-4222930-A VULCANIZABLE RUBBER, SILICEOUS FILLER DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-09-16 US disclosed
US-4152347-A REINFORCING AGENTS IN VULCANIZABLE RUBBER MIXTURES WHICH CONTAIN A SILICA FILLER DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-05-01 US disclosed
US-4144290-A Production of bromoaryl chlorophosphates BAYER AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4144290-A Production of bromoaryl chlorophosphates BAYER AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4016223-A Prostaglandin dehydrogenase inhibiting agents NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1977-04-05 US disclosed