SCHEMBL25192004 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	TRPC6	Q9Y210	5/20	0.38

▸	OPRK1	P41145	1/20	0.34

▸	NEK2	P51955	3/20	0.34

▸	MAPK1	P28482	1/20	0.34

▸	CETP	P11597	1/20	0.34

▸	CHRM4	P08173	4/20	0.33

▸	CHRM2	P08172	2/20	0.33

▸	CHRM1	P11229	2/20	0.33

▸	SLC6A9	P48067	1/20	0.33

▸	JAK3	P52333	2/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30420485	0.85	NR1H3 (0.43)	TRPC6
SCHEMBL25264927	0.85	CHRM4 (0.40)	CHRM4CHRM2CHRM1
SCHEMBL25189280	0.85	CHRM4 (0.40)	CHRM4CHRM2CHRM1
SCHEMBL19096956	0.77	USP30 (0.41)	OPRK1CHRM4CHRM2CHRM1
SCHEMBL20954167	0.77	USP30 (0.41)	OPRK1CHRM4CHRM2CHRM1
SCHEMBL20954154	0.77	USP30 (0.41)	OPRK1CHRM4CHRM2CHRM1
SCHEMBL16570434	0.75	GFER (0.47)	TRPC6OPRK1MAPK1
SCHEMBL25197760	0.75	IDO1 (0.40)	TRPC6MAPK1
SCHEMBL25188137	0.74	JAK3 (0.42)	TRPC6SLC6A9JAK3
SCHEMBL19096999	0.73	USP30 (0.43)	OPRK1CHRM4CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023086959-A1	FUSED TRIAZINONE DERIVATIVES AND METHODS OF USING THE SAME	RGENTA THERAPEUTICS, INC. (US)	2023-05-19	—	—	WO	disclosed