Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.56 |
| ▸ | BID | P55957 | 3/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.55 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.55 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | EP300 | Q09472 | 1/20 | 0.55 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.55 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.55 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL25188266 | 1.00 | PPARA (0.56) | PPARABIDMCL1BCL2L1BAK1 | |
| Acetic Acid SCHEMBL22500117 | 1.00 | PPARA (0.56) | PPARABIDMCL1BCL2L1BAK1 | |
| Acetic Acid SCHEMBL25188964 | 1.00 | PPARA (0.56) | PPARABIDMCL1BCL2L1BAK1 | |
| Acetic Acid SCHEMBL25190721 | 1.00 | PPARA (0.56) | PPARABIDMCL1BCL2L1BAK1 | |
| Acetic Acid SCHEMBL25193172 | 1.00 | PPARA (0.56) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL27594350 | 0.95 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL1838555 | 0.95 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL27513992 | 0.95 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL1835039 | 0.95 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL27543186 | 0.95 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023085225-A1 | METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION | 住友化学株式会社 | 2023-05-19 | — | — | WO | disclosed |