Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.63 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.63 |
| ▸ | LATS1 | O95835 | 11/20 | 0.57 |
| ▸ | LATS2 | Q9NRM7 | 8/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25193240 | 1.00 | TLR8 (0.63) | TLR8TLR7LATS1LATS2 | |
| SCHEMBL25191172 | 1.00 | TLR8 (0.63) | TLR8TLR7LATS1LATS2 | |
| SCHEMBL25189098 | 0.97 | TLR8 (0.64) | TLR8TLR7LATS1LATS2 | |
| SCHEMBL25265324 | 0.97 | TLR8 (0.64) | TLR8TLR7LATS1LATS2 | |
| SCHEMBL25184750 | 0.93 | TLR8 (0.61) | TLR8TLR7LATS1LATS2 | |
| SCHEMBL25184751 | 0.93 | TLR8 (0.61) | TLR8TLR7LATS1LATS2 | |
| SCHEMBL25194504 | 0.91 | TLR8 (0.63) | TLR8TLR7LATS1LATS2 | |
| SCHEMBL30376936 | 0.91 | TLR8 (0.63) | TLR8TLR7LATS1LATS2 | |
| SCHEMBL25266139 | 0.91 | TLR8 (0.63) | TLR8TLR7LATS1LATS2 | |
| SCHEMBL25184754 | 0.88 | LATS1 (0.61) | TLR8TLR7LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078241-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2023-05-11 | — | — | WO | disclosed |