Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.72 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.37 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25194886 | 1.00 | TLR8 (0.72) | TLR8TLR7KCNH2LATS1LATS2 | |
| SCHEMBL25191521 | 0.92 | TLR8 (0.70) | TLR8TLR7KCNH2LATS1LATS2 | |
| SCHEMBL25265229 | 0.88 | TLR8 (0.67) | TLR8TLR7KCNH2 | |
| SCHEMBL25190939 | 0.88 | TLR8 (0.67) | TLR8TLR7KCNH2 | |
| SCHEMBL18109449 | 0.83 | TLR8 (1.00) | TLR8TLR7KCNH2 | |
| SCHEMBL18109451 | 0.83 | TLR8 (1.00) | TLR8TLR7KCNH2 | |
| SCHEMBL25199509 | 0.82 | TLR8 (0.67) | TLR8TLR7KCNH2LATS1LATS2 | |
| SCHEMBL25265039 | 0.81 | TLR8 (0.67) | TLR8TLR7KCNH2LATS1LATS2 | |
| SCHEMBL25188606 | 0.81 | TLR8 (0.62) | TLR8TLR7KCNH2LATS1LATS2 | |
| SCHEMBL25192104 | 0.81 | TLR8 (0.67) | TLR8TLR7KCNH2LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472047-A | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-07-21 | — | — | CN | disclosed |
| WO-2023078241-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2023-05-11 | — | — | WO | disclosed |
| WO-2023078241-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2023-05-11 | — | — | WO | disclosed |