Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392297 | 1.00 | CYP11B1 (0.54) | CYP11B1SMPD1MAOBCYP11B2CYP19A1 | |
| SCHEMBL25418869 | 0.87 | EGFR (0.43) | MAOBEGFRPDE4BGSTP1ROCK2 | |
| SCHEMBL31481576 | 0.87 | EGFR (0.43) | MAOBEGFRPDE4BGSTP1ROCK2 | |
| SCHEMBL25419956 | 0.86 | MEN1 (0.51) | CYP11B1MAOBCYP11B2EGFRPDE4B | |
| SCHEMBL31481571 | 0.86 | MEN1 (0.51) | CYP11B1MAOBCYP11B2EGFRPDE4B | |
| SCHEMBL25196648 | 0.85 | CYP11B1 (0.43) | CYP11B1SMPD1MAOBCYP11B2NAAA | |
| SCHEMBL30390788 | 0.85 | CYP11B1 (0.43) | CYP11B1SMPD1MAOBCYP11B2NAAA | |
| SCHEMBL17714236 | 0.83 | CYP11B1 (0.68) | CYP11B1SMPD1MAOBCYP11B2PDE4B | |
| SCHEMBL25212479 | 0.83 | EGFR (0.48) | CYP11B1MAOBEGFRSPHK2LRRK2 | |
| SCHEMBL30392244 | 0.83 | EGFR (0.48) | CYP11B1MAOBEGFRSPHK2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091873-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-25 | — | — | WO | claimed |
| WO-2023091873-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023091873-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-25 | — | — | WO | disclosed |