Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29659142 | 0.72 | POLB (0.44) | GPR119PAX8 | |
| SCHEMBL6601505 | 0.72 | POLB (0.44) | GPR119PAX8 | |
| SCHEMBL15390791 | 0.70 | POLB (0.46) | GRM5GPR119 | |
| SCHEMBL30676280 | 0.70 | POLB (0.46) | GRM5GPR119 | |
| Methyl Alcohol SCHEMBL28902013 | 0.69 | GRM5 (0.67) | GRM5FFAR1CYP1A2 | |
| SCHEMBL13382197 | 0.69 | GRM5 (0.49) | GRM5FFAR1CYP1A2 | |
| SCHEMBL4676290 | 0.69 | HTR2C (0.49) | CYP1A2 | |
| SCHEMBL13382203 | 0.68 | GRM5 (0.45) | GRM5FFAR1 | |
| SCHEMBL30898830 | 0.68 | GRM5 (0.46) | GRM5FFAR1PTGDR2 | |
| SCHEMBL18104914 | 0.68 | FFAR1 (0.47) | GRM5FFAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667628-B2 | Compounds for imaging tau proteins that accumulate in brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2023-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667628-B2 | Compounds for imaging tau proteins that accumulate in brain | MAPT, FABP7, HTT | GRM5 2542/4885FFAR1 1755/4885CYP1A2 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.