Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.42 |
| ▸ | GSK3A | P49840 | 3/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.38 |
| ▸ | PRKACA | P17612 | 4/20 | 0.38 |
| ▸ | CDK8 | P49336 | 4/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30349241 | 1.00 | PRKCI (0.56) | PRKCIDYRK1ACLK4GSK3ARPS6KA3 | |
| SCHEMBL30347070 | 0.82 | PRKCI (0.51) | PRKCIDYRK1ACLK4GSK3ARPS6KA3 | |
| SCHEMBL25157602 | 0.82 | PRKCI (0.51) | PRKCIDYRK1ACLK4GSK3ARPS6KA3 | |
| SCHEMBL26174511 | 0.82 | PRKCI (0.66) | PRKCIDYRK1ACLK4GSK3ARPS6KA3 | |
| SCHEMBL30406657 | 0.80 | DYRK1A (0.48) | PRKCIDYRK1ARPS6KA5LATS1TBK1 | |
| SCHEMBL25158040 | 0.80 | PRKCI (0.51) | PRKCIDYRK1ACLK4GSK3ARPS6KA3 | |
| SCHEMBL25201242 | 0.80 | DYRK1A (0.48) | PRKCIDYRK1ARPS6KA5LATS1TBK1 | |
| SCHEMBL26174746 | 0.80 | PRKCI (0.54) | PRKCIDYRK1ACLK4GSK3ARPS6KA3 | |
| SCHEMBL26174664 | 0.80 | PRKCI (0.54) | PRKCIDYRK1ACLK4GSK3ARPS6KA3 | |
| SCHEMBL26174709 | 0.80 | PRKCI (0.54) | PRKCIDYRK1ACLK4GSK3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | claimed |
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | disclosed |
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | PRKCI 1043/4885DYRK1A 1/4885CLK4 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.