Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.73 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.61 |
| ▸ | LATS1 | O95835 | 1/20 | 0.56 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25184752 | 0.97 | TLR8 (0.68) | TLR8TLR7KCNH2LATS1LATS2 | |
| SCHEMBL25192103 | 0.93 | TLR8 (0.62) | TLR8TLR7KCNH2LATS1LATS2 | |
| SCHEMBL30608943 | 0.84 | TLR8 (1.00) | TLR8TLR7KCNH2 | |
| SCHEMBL30608978 | 0.84 | TLR8 (1.00) | TLR8TLR7KCNH2 | |
| SCHEMBL18109543 | 0.84 | TLR8 (1.00) | TLR8TLR7KCNH2 | |
| SCHEMBL18109290 | 0.84 | TLR8 (1.00) | TLR8TLR7KCNH2 | |
| SCHEMBL18109292 | 0.84 | TLR8 (1.00) | TLR8TLR7KCNH2 | |
| SCHEMBL30376965 | 0.83 | TLR8 (0.50) | TLR8TLR7KCNH2LATS1LATS2 | |
| SCHEMBL24384697 | 0.81 | KCNH2 (0.85) | TLR8TLR7KCNH2 | |
| SCHEMBL21325638 | 0.81 | KCNH2 (0.85) | TLR8TLR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472047-A | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-07-21 | — | — | CN | disclosed |
| WO-2023078241-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2023-05-11 | — | — | WO | disclosed |
| WO-2023078241-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2023-05-11 | — | — | WO | disclosed |