Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25194983 | 1.00 | SMPD1 (0.45) | SMPD1LTB4RPPARGPPARAVHL | |
| SCHEMBL25207691 | 1.00 | SMPD1 (0.45) | SMPD1LTB4RPPARGPPARAVHL | |
| SCHEMBL25211458 | 1.00 | SMPD1 (0.45) | SMPD1LTB4RPPARGPPARAVHL | |
| SCHEMBL25199391 | 1.00 | SMPD1 (0.45) | SMPD1LTB4RPPARGPPARAVHL | |
| SCHEMBL25202439 | 0.95 | SMPD1 (0.41) | SMPD1VHLTHRBHRH3ALDH1A1 | |
| SCHEMBL25594024 | 0.91 | SMPD1 (0.40) | SMPD1VHLTHRBALDH1A1POLB | |
| SCHEMBL21458950 | 0.91 | SMPD1 (0.41) | SMPD1VHL | |
| SCHEMBL25212361 | 0.90 | SMPD1 (0.40) | SMPD1LTB4R | |
| SCHEMBL25594025 | 0.88 | SMPD1 (0.56) | SMPD1PPARGPPARAALDH1A1 | |
| SCHEMBL21405008 | 0.86 | SMPD1 (0.42) | SMPD1VHLTHRBHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |