Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656439 | 1.00 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2D6HPGDCYP2C9 | |
| SCHEMBL31313272 | 1.00 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2D6HPGDCYP2C9 | |
| SCHEMBL31313342 | 1.00 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2D6HPGDCYP2C9 | |
| SCHEMBL29565211 | 1.00 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2D6HPGDCYP2C9 | |
| SCHEMBL10651740 | 1.00 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2D6HPGDCYP2C9 | |
| SCHEMBL25235601 | 1.00 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2D6HPGDCYP2C9 | |
| SCHEMBL2683268 | 1.00 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2D6HPGDCYP2C9 | |
| SCHEMBL28522760 | 0.99 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2D6HPGDCYP2C9 | |
| SCHEMBL28513121 | 0.99 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2D6HPGDCYP2C9 | |
| SCHEMBL3191884 | 0.93 | TRPV1 (0.67) | CYP1A2CYP3A4CYP2D6HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310351-A1 | REGIMEN FOR REPEATED TOPICAL APPLICATION OF CAPSAICIN PATCH | GRUENENTHAL GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| US-20230157977-A1 | REPEATED TOPICAL APPLICATION OF CAPSAICIN PATCH FOR TREATING INITIAL NON-RESPONDERS | GRUENENTHAL GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| CN-111647537-B | Salt-tolerant capsaicin degrading bacteria, application and kitchen waste treatment method | 浙江工业大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-111647536-B | High-temperature-resistant capsaicin degrading bacteria, application and kitchen waste treatment method | 浙江工业大学 | 2022-03-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230157977-A1 | REPEATED TOPICAL APPLICATION OF CAPSAICIN PATCH FOR TREATING INITIAL NON-RESPONDERS | TRPV1, NTRK1, GAP43 | CYP1A2 4549/4885CYP3A4 4603/4885CYP2D6 4123/4885 |
| US-20230310351-A1 | REGIMEN FOR REPEATED TOPICAL APPLICATION OF CAPSAICIN PATCH | TRPV1, PRPH, GAP43 | CYP1A2 3477/4885CYP3A4 4089/4885CYP2D6 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.