Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PRF1 | P14222 | 8/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450179 | 1.00 | MAPT (0.57) | MAPTLMNAGAAALDH1A1PRF1 | |
| SCHEMBL25218172 | 1.00 | MAPT (0.57) | MAPTLMNAGAAALDH1A1PRF1 | |
| SCHEMBL29450168 | 1.00 | MAPT (0.57) | MAPTLMNAGAAALDH1A1PRF1 | |
| SCHEMBL25266820 | 1.00 | MAPT (0.57) | MAPTLMNAGAAALDH1A1PRF1 | |
| SCHEMBL13797360 | 0.86 | MAPT (0.56) | MAPTLMNAGAAALDH1A1PRF1 | |
| SCHEMBL14177744 | 0.83 | MAPT (0.53) | MAPTLMNAGAAALDH1A1PRF1 | |
| SCHEMBL15157472 | 0.83 | MAPT (0.53) | MAPTLMNAGAAALDH1A1PRF1 | |
| SCHEMBL10286947 | 0.81 | MAPT (0.50) | MAPTLMNAGAAALDH1A1PRF1 | |
| SCHEMBL10064135 | 0.81 | MAPT (0.50) | MAPTLMNAGAAALDH1A1PRF1 | |
| SCHEMBL15195012 | 0.80 | PTGS1 (0.51) | MAPTLMNAGAAALDH1A1PRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188373-A1 | LOW MOLECULAR WEIGHT PROTEIN DEGRADERS AND THEIR APPLICATIONS | Captor Therapeutics S.A. (PL) | 2023-06-07 | — | — | EP | disclosed |
| WO-2022029138-A1 | LOW MOLECULAR WEIGHT PROTEIN DEGRADERS AND THEIR APPLICATIONS | CAPTOR THERAPEUTICS S.A. (PL) | 2022-02-10 | — | — | WO | disclosed |