Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 15/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25253136 | 0.98 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL8601458 | 0.91 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL8602800 | 0.91 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL8603837 | 0.91 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| Hydrochloric Acid SCHEMBL25255123 | 0.89 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL30639289 | 0.87 | SMN1; SMN2 (0.49) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL30896272 | 0.82 | SMN1; SMN2 (0.53) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL8795521 | 0.82 | SMN1; SMN2 (0.53) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL3298145 | 0.80 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL25273902 | 0.79 | SMN1; SMN2 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |