Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | RECQL | P46063 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | COMT | P21964 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445881 | 1.00 | MAPT (0.64) | MAPTSMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL25208344 | 0.94 | MAPT (0.62) | MAPTSMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL30445461 | 0.94 | MAPT (0.62) | MAPTSMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL30443231 | 0.93 | COMT (0.63) | MAPTSMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL25200815 | 0.93 | COMT (0.63) | MAPTSMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL25209809 | 0.86 | COMT (0.67) | MAPTSMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL30445866 | 0.86 | COMT (0.67) | MAPTSMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL25656244 | 0.85 | COMT (0.64) | MAPTSMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL25227519 | 0.85 | COMT (0.63) | MAPTSMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL30445938 | 0.85 | COMT (0.63) | MAPTSMN1; SMN2TP53KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153172-B1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NAT RECH SCIENT (FR) | 2024-11-27 | — | — | EP | disclosed |
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-08 | — | — | US | disclosed |
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-08 | — | — | US | disclosed |
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | TARBP1, NFATC1, TARDBP | MAPT 781/4885SMN1; SMN2 4842/4885TP53 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.