Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 4/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25273905 | 1.00 | BTK (0.46) | BTKCRBNDGAT2KLKB1CD69 | |
| SCHEMBL25248305 | 0.98 | BTK (0.46) | BTKCRBNDGAT2KLKB1ATR | |
| SCHEMBL25248307 | 0.98 | BTK (0.46) | BTKCRBNDGAT2KLKB1ATR | |
| SCHEMBL25262776 | 0.95 | BTK (0.47) | BTKCRBNDGAT2KLKB1 | |
| SCHEMBL25254966 | 0.92 | BTK (0.44) | BTKCRBNDGAT2KLKB1CD69 | |
| SCHEMBL29418528 | 0.92 | BTK (0.44) | BTKCRBNDGAT2KLKB1CD69 | |
| SCHEMBL29418525 | 0.92 | BTK (0.44) | BTKCRBNDGAT2KLKB1CD69 | |
| SCHEMBL25254965 | 0.92 | BTK (0.44) | BTKCRBNDGAT2KLKB1CD69 | |
| SCHEMBL25222586 | 0.90 | BTK (0.44) | BTKCRBNDGAT2KLKB1ATR | |
| SCHEMBL25270141 | 0.90 | BTK (0.44) | BTKCRBNDGAT2KLKB1ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |