Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392174 | 1.00 | SMPD1 (0.60) | SMPD1RAB9AMAOBCYP11B1CYP11B2 | |
| SCHEMBL25209295 | 0.90 | FFAR1 (0.50) | SMPD1MAOBCYP11B1CYP11B2MAOA | |
| SCHEMBL30392118 | 0.90 | FFAR1 (0.50) | SMPD1MAOBCYP11B1CYP11B2MAOA | |
| SCHEMBL25720539 | 0.86 | MAOB (0.64) | MAOBMAOAPTPN1NR4A2 | |
| SCHEMBL30391909 | 0.86 | MAOB (0.64) | MAOBMAOAPTPN1NR4A2 | |
| SCHEMBL25196861 | 0.84 | SMPD1 (0.62) | SMPD1RAB9AMAOBCYP11B1CYP11B2 | |
| SCHEMBL30391457 | 0.84 | SMPD1 (0.62) | SMPD1RAB9AMAOBCYP11B1CYP11B2 | |
| SCHEMBL25219976 | 0.83 | FFAR1 (0.47) | RAB9AMAOBPTPN1FFAR1NR4A2 | |
| SCHEMBL30392078 | 0.83 | FFAR1 (0.47) | RAB9AMAOBPTPN1FFAR1NR4A2 | |
| SCHEMBL25720255 | 0.81 | HPGD (0.49) | RAB9AALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091873-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023091873-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-25 | — | — | WO | disclosed |