Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 20/20 | 0.86 |
| ▸ | PIK3CD | O00329 | 18/20 | 0.86 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.86 |
| ▸ | PIK3R2 | O00459 | 13/20 | 0.85 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.73 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25418991 | 0.94 | PIK3CG (0.86) | PIK3CGPIK3CDPIK3R1PIK3R2PIK3CA | |
| SCHEMBL23678048 | 0.92 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3R1PIK3R2PIK3CA | |
| SCHEMBL15307164 | 0.92 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3R1PIK3R2PIK3CA | |
| SCHEMBL15306895 | 0.92 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3R1PIK3R2PIK3CA | |
| SCHEMBL16628946 | 0.92 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3R1PIK3R2PIK3CA | |
| SCHEMBL16629005 | 0.92 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3R1PIK3R2PIK3CA | |
| SCHEMBL15306899 | 0.91 | PIK3CG (0.88) | PIK3CGPIK3CDPIK3R1PIK3R2PIK3CA | |
| SCHEMBL25420884 | 0.89 | PIK3CG (0.91) | PIK3CGPIK3CDPIK3R1PIK3R2PIK3CA | |
| SCHEMBL30524377 | 0.89 | PIK3CG (0.91) | PIK3CGPIK3CDPIK3R1PIK3R2PIK3CA | |
| SCHEMBL16629001 | 0.89 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3R1PIK3R2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096850-A1 | PHOSPHOINOSITIDE 3 KINASE GAMMA INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | GEODE THERAPEUTICS INC. (US) | 2023-06-01 | — | — | WO | disclosed |