Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117309 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL11695805 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL2341027 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL2178335 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL50789 | 1.00 | — | — | |
| SCHEMBL4195383 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL2175777 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL5974474 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL10320275 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL134259 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063220-A | Preparation method of silodosin | 山西库邦生物医药科技有限公司 | 2023-05-05 | — | — | CN | claimed |
| EP-4192839-A1 | REMDESIVIR INTERMEDIATES | Richter Gedeon Nyrt. (HU) | 2023-06-14 | — | — | EP | disclosed |
| CN-116063220-A | Preparation method of silodosin | 山西库邦生物医药科技有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-113620869-B | Preparation method of betrixaban | 江西同和药业股份有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-113620869-A | Preparation method of betrixaban | 江西同和药业股份有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-107445932-A | The preparation technology of Dapagliflozin eutectic thing | 上海医药工业研究院 | 2017-12-08 | — | — | CN | disclosed |
| CN-106188022-A | The preparation method that Yi Gelie is clean | 上海医药工业研究院 | 2016-12-07 | — | — | CN | disclosed |
| CN-103261161-B | The crystallized form of coagulation factor xa inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2016-04-27 | — | — | CN | disclosed |
| CN-103261161-A | Crystalline forms of a factor Xa inhibitor | PORTOLA PHARM INC | 2013-08-21 | — | — | CN | disclosed |