SCHEMBL252218

SCHEMBL252218

C=CCC(O)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11876443 0.74
SCHEMBL251547 0.71
SCHEMBL29622 0.71
SCHEMBL11878626 0.71
SCHEMBL1252355 0.69
SCHEMBL2486474 0.69
SCHEMBL11032450 0.69
SCHEMBL252217 0.69
SCHEMBL7489731 0.69
SCHEMBL9786703 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4301381-A1 COMPOSITIONS AND METHODS FOR MODULATING EPITHELIAL-MESENCHYMAL TRANSITION Auckland Uniservices Limited (NZ) 2024-01-10 EP claimed
WO-2022187387-A9 COMPOSITIONS AND METHODS FOR MODULATING EPITHELIAL-MESENCHYMAL TRANSITION AUCKLAND UNISERVICES LIMITED (NZ) 2023-10-05 WO claimed
WO-2022187387-A1 COMPOSITIONS AND METHODS FOR MODULATING EPITHELIAL-MESENCHYMAL TRANSITION AUCKLAND UNISERVICES LIMITED (NZ) 2022-09-09 WO claimed
EP-4027992-A1 COMPOSITIONS AND METHODS FOR RESCUING RETINAL AND CHOROIDAL STRUCTURE AND FUNCTION Auckland Uniservices Limited (NZ) 2022-07-20 EP claimed
US-11344603-B2 Cytokine modulation AUCKLAND UNISERVICES LIMITED (NZ) 2022-05-31 US claimed
CN-112029084-B Simple and controllable method for synthesizing alpha-mercapto-omega-hydroxyl polyether by taking thiocarboxylic acid as initiator 华南理工大学 2021-10-26 CN claimed
WO-2021051015-A1 COMPOSITIONS AND METHODS FOR RESCUING RETINAL AND CHOROIDAL STRUCTURE AND FUNCTION AUCKLAND UNISERVICES LIMITED (NZ) 2021-03-18 WO claimed
CN-112029084-A Simple and controllable method for synthesizing alpha-mercapto-omega-hydroxyl polyether by taking thiocarboxylic acid as initiator 华南理工大学 2020-12-04 CN claimed
US-10465188-B2 Channel modulators AUCKLAND UNISERVICES LIMITED (NZ) 2019-11-05 US claimed
CN-109415297-A New antibiotic 布洛斯 & 库珀制药私人有限公司 2019-03-01 CN claimed
EP-0126367-A1 Chroman and chromene derivatives BEECHAM GROUP PLC (GB) 1984-11-28 EP claimed
EP-0126350-A1 Novel compounds BEECHAM GROUP PLC (GB) 1984-11-28 EP claimed
EP-0126311-A2 Benzopyran derivatives. BEECHAM GROUP PLC (GB) 1984-11-28 EP claimed
US-4481214-A 4-Acylaminobenzopyrans useful as anti-hypertensive agents BEECHAM GROUP P.L.C. (GB) 1984-11-06 US claimed
EP-0120426-A1 Antihypertensive benzopyrons BEECHAM GROUP PLC (GB) 1984-10-03 EP claimed
EP-0120427-A1 3,4-Dihydro-thiaoxo-1-pyrrolidinyl-or piperidinyl-ZH-benzo[b]pyrons BEECHAM GROUP PLC (GB) 1984-10-03 EP claimed
EP-0107423-A1 Novel chromans and chromenes BEECHAM GROUP PLC (GB) 1984-05-02 EP claimed
EP-0095316-A1 Pharmaceutically active aminobenzopyrans BEECHAM GROUP PLC (GB) 1983-11-30 EP claimed
EP-0093534-A1 Novel chromanols BEECHAM GROUP PLC (GB) 1983-11-09 EP claimed
EP-0093535-A1 Novel chromenes and chromans BEECHAM GROUP PLC (GB) 1983-11-09 EP claimed