Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26322229 | 0.94 | HSD17B10 (0.54) | CYP1A2CYP3A4HSD17B10MAOAADRA2A | |
| SCHEMBL2168131 | 0.92 | CYP1A2 (0.66) | CYP1A2CYP3A4HSD17B10MAOAADRA2A | |
| SCHEMBL1921953 | 0.90 | CYP1A2 (0.64) | CYP1A2CYP3A4HSD17B10MAOAADRA2A | |
| SCHEMBL23561265 | 0.89 | CYP3A4 (0.55) | CYP1A2CYP3A4HSD17B10MAOAADRA2A | |
| SCHEMBL19836623 | 0.89 | CYP1A2 (0.50) | CYP1A2CYP3A4HSD17B10MAOAADRA2A | |
| SCHEMBL2165580 | 0.86 | CYP1A2 (0.60) | CYP1A2CYP3A4HSD17B10MAOAADRA2A | |
| SCHEMBL1921940 | 0.85 | CYP1A2 (0.58) | CYP1A2CYP3A4HSD17B10MAOAADRA2A | |
| SCHEMBL20034967 | 0.84 | CYP1A2 (0.54) | CYP1A2CYP3A4HSD17B10MAOAADRA2A | |
| Fluorene SCHEMBL5425556 | 0.82 | CYP3A4 (0.60) | CYP1A2CYP3A4HSD17B10MAOAADRA2A | |
| SCHEMBL1921956 | 0.82 | CYP1A2 (0.60) | CYP1A2CYP3A4HSD17B10MAOAADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039128-B2 | Fluorene compound, organic light emitting device and display device using the fluorene compound | CANON KABUSHIKI KAISHA (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20100072885-A1 | FLUORENE COMPOUND, ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE USING THE FLUORENE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100072885-A1 | FLUORENE COMPOUND, ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE USING THE FLUORENE COMPOUND | ARL1, AFF1, AFF2 | CYP1A2 214/4885CYP3A4 825/4885HSD17B10 2450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.