Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25649311 | 0.94 | BTK (0.50) | BTK | |
| SCHEMBL30449342 | 0.94 | BTK (0.50) | BTK | |
| SCHEMBL25277091 | 0.91 | BTK (0.54) | BTK | |
| SCHEMBL21903677 | 0.90 | BTK (0.47) | BTK | |
| SCHEMBL21903674 | 0.90 | BTK (0.47) | BTK | |
| SCHEMBL25225388 | 0.90 | BTK (0.45) | BTK | |
| SCHEMBL30449214 | 0.90 | BTK (0.45) | BTK | |
| SCHEMBL25226368 | 0.89 | BTK (0.44) | BTK | |
| SCHEMBL21903833 | 0.88 | BTK (0.45) | BTK | |
| SCHEMBL21903831 | 0.88 | BTK (0.45) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110970-A1 | MACROCYCLIC BTK INHIBITORS | NETHERLANDS TRANSLATIONAL RESEARCH CENTER HOLDING B.V (NL) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023110936-A1 | REVERSIBLE MACROCYCLIC KINASE INHIBITORS | NETHERLANDS TRANSLATIONAL RESEARCH CENTER HOLDING B.V (NL) | 2023-06-22 | — | — | WO | disclosed |