Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449660 | 1.00 | BTK (0.40) | BTK | |
| SCHEMBL30449584 | 0.97 | BTK (0.38) | BTK | |
| SCHEMBL30497625 | 0.92 | BTK (0.41) | BTK | |
| SCHEMBL25227103 | 0.92 | BTK (0.41) | BTK | |
| SCHEMBL30449124 | 0.84 | BTK (0.43) | BTK | |
| SCHEMBL25649252 | 0.84 | BTK (0.43) | BTK | |
| SCHEMBL25647777 | 0.82 | MAPT (0.38) | — | |
| SCHEMBL31125830 | 0.82 | MAPT (0.38) | — | |
| SCHEMBL25228047 | 0.81 | BTK (0.46) | BTK | |
| SCHEMBL25240799 | 0.81 | BTK (0.46) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110936-A1 | REVERSIBLE MACROCYCLIC KINASE INHIBITORS | NETHERLANDS TRANSLATIONAL RESEARCH CENTER HOLDING B.V (NL) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023110936-A1 | REVERSIBLE MACROCYCLIC KINASE INHIBITORS | NETHERLANDS TRANSLATIONAL RESEARCH CENTER HOLDING B.V (NL) | 2023-06-22 | — | — | WO | disclosed |