Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.39 |
| ▸ | CA2 | P00918 | 9/20 | 0.39 |
| ▸ | CA9 | Q16790 | 7/20 | 0.39 |
| ▸ | CA7 | P43166 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30466332 | 1.00 | CA1 (0.39) | CA1CA2CA9CA7CA12 | |
| SCHEMBL25277048 | 1.00 | CA1 (0.39) | CA1CA2CA9CA7CA12 | |
| SCHEMBL25279448 | 0.89 | HTT (0.37) | ALDH1A1MAPTPOLBMCOLN3HTT | |
| SCHEMBL30466277 | 0.89 | HTT (0.37) | ALDH1A1MAPTPOLBMCOLN3HTT | |
| SCHEMBL25279449 | 0.89 | HTT (0.37) | ALDH1A1MAPTPOLBMCOLN3HTT | |
| SCHEMBL25729174 | 0.79 | CA12 (0.41) | CA1CA2CA9CA7CA12 | |
| SCHEMBL30466283 | 0.78 | KMT2A (0.40) | ALDH1A1MAPTPOLBMCOLN3HTT | |
| SCHEMBL25271933 | 0.78 | KMT2A (0.40) | ALDH1A1MAPTPOLBMCOLN3HTT | |
| SCHEMBL25271934 | 0.78 | KMT2A (0.40) | ALDH1A1MAPTPOLBMCOLN3HTT | |
| SCHEMBL25274194 | 0.76 | NR1H2 (0.33) | CA1CA2CA9CA7CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448105-A1 | HETEROCYCLE DERIVATIVES FOR THE TREATMENT OF DISEASE | VIR Biotechnology, Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114428-A1 | HETEROCYCLE DERIVATIVES FOR THE TREATMENT OF DISEASE | Vir Biotechnology, Inc. (US) | 2023-06-22 | — | — | WO | disclosed |