SCHEMBL25232020

SCHEMBL25232020

Clc1ccc2nn(Cl)nc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.46
F3 P13726 1/20 0.46
DYRK1A Q13627 1/20 0.46
MAPT P10636 3/20 0.44
KDM4E B2RXH2 3/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ATM Q13315 1/20 0.44
PIK3CG P48736 2/20 0.41
CHEK1 O14757 1/20 0.39
LIMK1 P53667 1/20 0.39
MAPK14 Q16539 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
NR4A2 P43354 3/20 0.38
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 2/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10912104 0.79 KDM4E (0.47) F7F3DYRK1AMAPTKDM4E
SCHEMBL12126371 0.79 F7 (0.45) F7F3DYRK1AMAPTKDM4E
SCHEMBL28818202 0.74 NQO2 (0.45) MAPTKDM4ENPC1RAB9ATDP1
SCHEMBL28837679 0.74 F7 (0.41) F7F3DYRK1AMAPTKDM4E
Phosphoric Acid SCHEMBL3486158 0.71 KDM4E (0.41) F7F3DYRK1AMAPTKDM4E
SCHEMBL11459783 0.71 NPC1 (0.53) F7F3DYRK1AMAPTKDM4E
SCHEMBL15255810 0.70 F7 (0.37) F7F3DYRK1AMAPTKDM4E
SCHEMBL205108 0.70 HPGD (0.38) F7F3DYRK1AMAPTKDM4E
SCHEMBL11418479 0.70 NPC1 (0.51) F7F3DYRK1AMAPTKDM4E
SCHEMBL11332544 0.70 NPC1 (0.56) F7F3DYRK1AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023122498-A1 ONE-STEP OXIDE BATH FOR IMPROVING ADHESION OF POLYMERIC MATERIALS TO METAL SUBSTRATES MACDERMID, INCORPORATED (US) 2023-06-29 WO claimed
US-20230199972-A1 One-Step Oxide Bath for Improving Adhesion of Polymeric Materials to Metal Substrates MACDERMID, INCORPORATED 2023-06-22 US claimed
WO-2023122498-A1 ONE-STEP OXIDE BATH FOR IMPROVING ADHESION OF POLYMERIC MATERIALS TO METAL SUBSTRATES MACDERMID, INCORPORATED (US) 2023-06-29 WO disclosed
US-20230199972-A1 One-Step Oxide Bath for Improving Adhesion of Polymeric Materials to Metal Substrates MACDERMID, INCORPORATED 2023-06-22 US disclosed
CN-114096377-A Flux, rosin-cored solder using flux, flux-coated solder using flux, and soldering method 千住金属工业株式会社 2022-02-25 CN disclosed