Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 13/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | MST1R | Q04912 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288635 | 0.86 | TYK2 (0.40) | TYK2PIK3CAPIK3C3 | |
| SCHEMBL25292519 | 0.85 | TYK2 (0.39) | TYK2PIK3CAPIK3C3 | |
| SCHEMBL25238145 | 0.85 | TYK2 (0.39) | TYK2PIK3CAPIK3C3 | |
| SCHEMBL25289699 | 0.85 | TYK2 (0.40) | TYK2PIK3CAPIK3C3 | |
| SCHEMBL25242170 | 0.85 | TYK2 (0.39) | TYK2PIK3CAPIK3C3 | |
| SCHEMBL25288619 | 0.85 | TYK2 (0.42) | TYK2PIK3CAPIK3C3TTK | |
| SCHEMBL25288710 | 0.84 | TYK2 (0.40) | TYK2PIK3CAPIK3C3 | |
| SCHEMBL25289205 | 0.84 | TYK2 (0.39) | TYK2PIK3CAPIK3C3 | |
| SCHEMBL25242794 | 0.84 | TYK2 (0.39) | TYK2PIK3CAPIK3C3 | |
| SCHEMBL25290632 | 0.84 | TYK2 (0.39) | TYK2PIK3CAPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |