Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 20/20 | 0.67 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.52 |
| ▸ | CLK2 | P49760 | 3/20 | 0.52 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | GAK | O14976 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.52 |
| ▸ | ULK1 | O75385 | 1/20 | 0.52 |
| ▸ | STK10 | O94804 | 1/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.52 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | TYK2 | P29597 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25254708 | 0.92 | CSNK2A1 (0.80) | CSNK2A1 | |
| SCHEMBL25286346 | 0.89 | CSNK2A1 (0.84) | CSNK2A1CSNK2A2CSNK2BCLK2CSNK2A3 | |
| SCHEMBL25286410 | 0.84 | CSNK2A1 (0.64) | CSNK2A1CSNK2A2CSNK2BCLK2CSNK2A3 | |
| SCHEMBL30486965 | 0.82 | CSNK2A1 (0.52) | CSNK2A1CSNK2A2CSNK2BCLK2CSNK2A3 | |
| SCHEMBL25246507 | 0.82 | CSNK2A1 (0.68) | CSNK2A1CSNK2A2CSNK2BCLK2CSNK2A3 | |
| SCHEMBL10132503 | 0.81 | CSNK2A1 (1.00) | CSNK2A1 | |
| SCHEMBL10132495 | 0.80 | CSNK2A1 (0.79) | CSNK2A1 | |
| SCHEMBL25422529 | 0.80 | CSNK2A1 (0.64) | CSNK2A1CSNK2A2CSNK2BCLK2CSNK2A3 | |
| SCHEMBL2689292 | 0.80 | CSNK2A1 (0.80) | CSNK2A1CSNK2A2CSNK2BCLK2CSNK2A3 | |
| SCHEMBL25247670 | 0.80 | CSNK2A1 (0.73) | CSNK2A1CSNK2A2CSNK2BCLK2CSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126951-A1 | INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023126951-A1 | INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-07-06 | — | — | WO | disclosed |