⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252353 | 0.95 | GAA (0.31) | — | |
| SCHEMBL26771292 | 0.88 | GAA (0.30) | — | |
| SCHEMBL25243154 | 0.88 | — | — | |
| Formic Acid SCHEMBL25248310 | 0.86 | PRMT5 (0.34) | — | |
| Formic Acid SCHEMBL25266827 | 0.81 | — | — | |
| SCHEMBL24252344 | 0.80 | PRMT5 (0.35) | — | |
| SCHEMBL24252386 | 0.80 | — | — | |
| Formic Acid SCHEMBL25255492 | 0.78 | PLG (0.31) | — | |
| Formic Acid SCHEMBL25303310 | 0.76 | PLG (0.32) | — | |
| Formic Acid SCHEMBL30462760 | 0.76 | PLG (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070932-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON INC (US) | 2026-03-12 | — | — | US | disclosed |
| US-12509474-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-20240109920-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2024-04-04 | — | — | US | disclosed |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |