Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 5/20 | 0.76 |
| ▸ | ESR1 | P03372 | 9/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.70 |
| ▸ | ESRRG | P62508 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | HTR6 | P50406 | 2/20 | 0.70 |
| ▸ | PGR | P06401 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.70 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | EGFR | P00533 | 1/20 | 0.70 |
| ▸ | GBA1 | P04062 | 1/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25701928 | 1.00 | ESRRB (0.76) | ESRRBESR1ESR2ESRRGMAPT | |
| SCHEMBL25236775 | 0.90 | ESR1 (0.74) | ESRRBESR1ESR2ESRRGMAPT | |
| SCHEMBL25701930 | 0.90 | ESR1 (0.74) | ESRRBESR1ESR2ESRRGMAPT | |
| SCHEMBL20533979 | 0.86 | ESRRB (1.00) | ESRRBESR1ESR2ESRRGMAPT | |
| Tamoxifen SCHEMBL28507550 | 0.85 | ESR1 (0.92) | ESRRBESR1ESR2ESRRGMAPT | |
| Tamoxifen SCHEMBL2412107 | 0.84 | ESR1 (0.90) | ESRRBESR1ESR2ESRRGMAPT | |
| Tamoxifen SCHEMBL2412102 | 0.84 | ESR1 (0.90) | ESRRBESR1ESR2ESRRGMAPT | |
| Tamoxifen SCHEMBL17262082 | 0.83 | ESR1 (1.00) | ESRRBESR1ESR2ESRRGMAPT | |
| Tamoxifen SCHEMBL1056785 | 0.83 | ESR1 (1.00) | ESRRBESR1ESR2ESRRGMAPT | |
| SCHEMBL29659348 | 0.83 | ESR1 (1.00) | ESRRBESR1ESR2ESRRGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023112055-A1 | NEW SYNTHETIC PROCESS DESIGN FOR THE SYNTHESIS OF CARBOXY TORMIFENE AND PURITY ANALYSIS TO STRENGTHEN ANTIDOPING TESTING | DIRECTOR, NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH, GUWAHATI (NIPER-G) (IN) | 2023-06-22 | — | — | WO | claimed |
| WO-2023112055-A1 | NEW SYNTHETIC PROCESS DESIGN FOR THE SYNTHESIS OF CARBOXY TORMIFENE AND PURITY ANALYSIS TO STRENGTHEN ANTIDOPING TESTING | DIRECTOR, NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH, GUWAHATI (NIPER-G) (IN) | 2023-06-22 | — | — | WO | disclosed |