Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245254 | 0.98 | TYK2 (0.48) | TYK2JAK1 | |
| SCHEMBL25293502 | 0.88 | TYK2 (0.48) | TYK2JAK1 | |
| SCHEMBL25286935 | 0.87 | TYK2 (0.46) | TYK2JAK1MMP13 | |
| SCHEMBL25288583 | 0.86 | TYK2 (0.47) | TYK2JAK1 | |
| SCHEMBL25247928 | 0.86 | TYK2 (0.49) | TYK2JAK1 | |
| SCHEMBL25241803 | 0.84 | TYK2 (0.55) | TYK2JAK1 | |
| SCHEMBL25245561 | 0.83 | TYK2 (0.50) | TYK2JAK1 | |
| SCHEMBL25289234 | 0.81 | TYK2 (0.57) | TYK2JAK1 | |
| SCHEMBL25289314 | 0.79 | TYK2 (0.69) | TYK2JAK1 | |
| SCHEMBL25292444 | 0.79 | TYK2 (0.52) | TYK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |