Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487391 | 1.00 | KCNQ2 (0.48) | KCNQ2RAB9AMAOBMAPTLMNA | |
| SCHEMBL30487409 | 0.93 | KCNQ2 (0.46) | KCNQ2RAB9AMAOBMAPTLMNA | |
| SCHEMBL25243902 | 0.93 | KCNQ2 (0.46) | KCNQ2RAB9AMAOBMAPTLMNA | |
| SCHEMBL25285856 | 0.92 | KCNQ2 (0.47) | KCNQ2RAB9AMAOBMAPTLMNA | |
| SCHEMBL30487416 | 0.90 | KCNQ2 (0.39) | KCNQ2RAB9AMAOBMAPTLMNA | |
| SCHEMBL25254811 | 0.88 | KCNQ2 (0.41) | KCNQ2RAB9AMAOBMAPTLMNA | |
| SCHEMBL31020091 | 0.88 | KCNQ2 (0.41) | KCNQ2RAB9AMAOBMAPTLMNA | |
| SCHEMBL25245481 | 0.87 | KCNQ2 (0.42) | KCNQ2RAB9AMAOBMAPTLMNA | |
| SCHEMBL25244199 | 0.87 | KCNQ2 (0.40) | KCNQ2RAB9AMAOBMAPTLMNA | |
| SCHEMBL30487428 | 0.87 | KCNQ2 (0.42) | KCNQ2RAB9AMAOBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067819-A1 | PIPERIDINE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2024-04-04 | — | — | WO | disclosed |
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |