Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.52 |
| ▸ | SRC | P12931 | 4/20 | 0.52 |
| ▸ | ERBB4 | Q15303 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | LCK | P06239 | 3/20 | 0.52 |
| ▸ | RET | P07949 | 3/20 | 0.52 |
| ▸ | MET | P08581 | 3/20 | 0.52 |
| ▸ | LTK | P29376 | 3/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | MAP4K5 | Q9Y4K4 | 3/20 | 0.52 |
| ▸ | KIT | P10721 | 3/20 | 0.52 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | FYN | P06241 | 2/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246210 | 0.85 | HDAC1 (0.60) | EGFRERBB2SRCHDAC1LCK | |
| Hydrochloric Acid SCHEMBL2052117 | 0.84 | EGFR (0.71) | EGFRERBB2SRCERBB4LCK | |
| SCHEMBL25370207 | 0.84 | EGFR (0.73) | EGFRERBB2SRCERBB4LCK | |
| SCHEMBL3240234 | 0.83 | EGFR (0.70) | EGFRERBB2SRCHDAC1KDR | |
| SCHEMBL25244132 | 0.83 | EGFR (0.53) | EGFRERBB2KDRAURKBPDGFRB | |
| SCHEMBL25369245 | 0.81 | EGFR (0.68) | EGFRERBB2SRCERBB4LCK | |
| SCHEMBL25267376 | 0.80 | EGFR (0.45) | EGFRERBB2ERBB4KDRAURKB | |
| Hydrochloric Acid SCHEMBL2052116 | 0.80 | EGFR (0.69) | EGFRERBB2SRCERBB4LCK | |
| SCHEMBL26056425 | 0.80 | EGFR (0.64) | EGFRERBB2SRCERBB4LCK | |
| SCHEMBL26055503 | 0.78 | EGFR (0.52) | EGFRERBB2SRCERBB4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4194443-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |