Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25771610 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL30547995 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL25771608 | 0.88 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL25285821 | 0.88 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL25774761 | 0.84 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL25771634 | 0.84 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL25285899 | 0.84 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL25287716 | 0.79 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL25771694 | 0.79 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL25293936 | 0.79 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447954-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | Icahn School of Medicine at Mount Sinai (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114472-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-06-22 | — | — | WO | disclosed |