Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25240499 | 0.93 | PDE10A (0.37) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25261050 | 0.88 | — | — | |
| Formic Acid SCHEMBL30467631 | 0.87 | FEN1 (0.33) | FEN1PIK3CDPIK3CAPIK3CBPIK3CG | |
| Formic Acid SCHEMBL25250167 | 0.87 | FEN1 (0.33) | FEN1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL24252672 | 0.86 | FEN1 (0.36) | FEN1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26771374 | 0.84 | FEN1 (0.35) | FEN1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25260379 | 0.84 | — | — | |
| SCHEMBL25257323 | 0.83 | — | — | |
| SCHEMBL25260480 | 0.82 | PDE10A (0.31) | — | |
| SCHEMBL25304165 | 0.82 | PDE10A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109920-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2024-04-04 | — | — | US | disclosed |
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109920-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | CFB, CFH, C9 | FEN1 2638/4885PIK3CD 1808/4885PIK3CA 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.