Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 1.00 |
| ▸ | RIPK2 | O43353 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | BRAF | P15056 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | FLT3 | P36888 | 1/20 | 1.00 |
| ▸ | CLK1 | P49759 | 1/20 | 1.00 |
| ▸ | IRAK1 | P51617 | 1/20 | 1.00 |
| ▸ | RIPK1 | Q13546 | 1/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 1/20 | 1.00 |
| ▸ | STK38 | Q15208 | 1/20 | 1.00 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 1.00 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30428189 | 1.00 | IRAK4 (1.00) | IRAK4RIPK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25298174 | 1.00 | IRAK4 (1.00) | IRAK4RIPK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25297658 | 1.00 | IRAK4 (1.00) | IRAK4RIPK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30427723 | 1.00 | IRAK4 (1.00) | IRAK4RIPK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25245097 | 0.93 | IRAK4 (1.00) | IRAK4RIPK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25297787 | 0.91 | IRAK4 (1.00) | IRAK4RIPK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30428343 | 0.91 | IRAK4 (1.00) | IRAK4RIPK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25298434 | 0.91 | IRAK4 (1.00) | IRAK4RIPK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25298740 | 0.91 | IRAK4 (1.00) | IRAK4RIPK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25793298 | 0.91 | IRAK4 (1.00) | IRAK4RIPK2CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074919-A1 | Heteroaryl compounds as inhibitors of irak4, compositions and applications thereof | ACCRO BIOSCIENCE HK LTD (HK) | 2025-03-06 | — | — | US | disclosed |
| WO-2023130054-A2 | HETEROARYL COMPOUNDS AS INHIBITORS OF IRAK4, COMPOSITIONS AND APPLICATIONS THEREOF | ACCRO BIOSCIENCE (HK) LIMITED (CN) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023130054-A2 | HETEROARYL COMPOUNDS AS INHIBITORS OF IRAK4, COMPOSITIONS AND APPLICATIONS THEREOF | ACCRO BIOSCIENCE (HK) LIMITED (CN) | 2023-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074919-A1 | Heteroaryl compounds as inhibitors of irak4, compositions and applications thereof | IRAK4, IRAK1, IRAK2 | IRAK4 1/4885RIPK2 30/4885CYP1A2 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.