Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529628 | 0.90 | ELANE (0.42) | AOC3ELANELMNABCHERAB9A | |
| SCHEMBL2532586 | 0.88 | ELANE (0.55) | AOC3ELANELMNABCHEHIF1A | |
| SCHEMBL2529281 | 0.87 | ESR1 (0.49) | AOC3ELANEBCHEHIF1AESR1 | |
| SCHEMBL2527485 | 0.86 | ELANE (0.43) | AOC3ELANELMNABCHERAB9A | |
| SCHEMBL2529249 | 0.85 | AOC3 (0.37) | AOC3ELANEBCHEHIF1AESR1 | |
| SCHEMBL2532007 | 0.85 | BCL9 (0.41) | AOC3ELANELMNABCHEHIF1A | |
| SCHEMBL2527786 | 0.84 | BCHE (0.42) | AOC3ELANEBCHEKDM4ESLC6A3 | |
| SCHEMBL2525241 | 0.84 | KMT2A (0.51) | SLC6A3RAB9AMAPTPKMCYP2D6 | |
| SCHEMBL2532624 | 0.83 | TAAR1 (0.39) | AOC3HIF1AKDM4ECYP2C9TSHR | |
| SCHEMBL2529496 | 0.83 | KMT2A (0.37) | AOC3ELANELMNABCHEHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
| US-4108973-A | OXIDATION | HOFFMANN-LA ROCHE INC. (US) | 1978-08-22 | — | — | US | disclosed |
| US-4041076-A | USEFUL IN PREPARING ANTIGENS; N-(2-(4-HYDROXYPHENYL)ETHYL)-2-(4-(2-AMINOPROPYL)-PHENOXY) ACETAMIDES | HOFFMANN-LA ROCHE INC. (US) | 1977-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | AOC3 2105/4885ELANE 270/4885LMNA 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.