Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 10/20 | 0.49 |
| ▸ | JAK3 | P52333 | 8/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | JAK1 | P23458 | 2/20 | 0.44 |
| ▸ | TYK2 | P29597 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531118 | 0.93 | STAT6 (0.48) | STAT6JAK3IRAK4JAK2JAK1 | |
| SCHEMBL12301519 | 0.87 | STAT6 (0.55) | STAT6JAK3IRAK4JAK2JAK1 | |
| SCHEMBL2525177 | 0.85 | STAT6 (0.49) | STAT6JAK3IRAK4JAK2JAK1 | |
| SCHEMBL2475291 | 0.85 | STAT6 (0.49) | STAT6JAK3IRAK4JAK2JAK1 | |
| SCHEMBL2479483 | 0.84 | STAT6 (0.48) | STAT6JAK3IRAK4JAK2JAK1 | |
| SCHEMBL2531120 | 0.84 | STAT6 (0.48) | STAT6JAK3IRAK4JAK2JAK1 | |
| SCHEMBL12301702 | 0.84 | STAT6 (0.52) | STAT6JAK3IRAK4JAK2JAK1 | |
| SCHEMBL12301564 | 0.83 | STAT6 (0.55) | STAT6JAK3IRAK4JAK2JAK1 | |
| SCHEMBL12301523 | 0.83 | STAT6 (0.50) | STAT6JAK3IRAK4JAK2JAK1 | |
| SCHEMBL2476949 | 0.82 | STAT6 (0.56) | STAT6JAK3IRAK4JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102227409-B | Pyridine-3-carboxyamide derivative | KOWA CO | 2014-03-26 | — | — | CN | disclosed |
| EP-2380877-A1 | PYRIDINE-3-CARBOXYAMIDE DERIVATIVE | Kowa Company, Ltd. (JP) | 2011-10-26 | — | — | EP | disclosed |