⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5985912 | 0.78 | — | — | |
| SCHEMBL5985909 | 0.78 | — | — | |
| SCHEMBL8036549 | 0.76 | — | — | |
| SCHEMBL2120913 | 0.76 | — | — | |
| SCHEMBL21634420 | 0.76 | — | — | |
| SCHEMBL8036555 | 0.76 | — | — | |
| SCHEMBL2120908 | 0.76 | — | — | |
| SCHEMBL15371824 | 0.75 | — | — | |
| SCHEMBL11764919 | 0.74 | — | — | |
| SCHEMBL12239667 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039465-B2 | Cytoskeletal active compounds, composition and use | INSPIRE PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| US-20100130572-A1 | CYTOSKELETAL ACTIVE COMPOUNDS, COMPOSITION AND USE | LAMPE JOHN W | 2010-05-27 | — | — | US | disclosed |
| US-7320974-B2 | Cytoskeletal active compounds, compositions and use | INSPIRE PHARMACEUTICALS, INC. (US) | 2008-01-22 | — | — | US | disclosed |
| EP-1866316-A2 | CYTOSKELETAL ACTIVE COMPOUNDS, COMPOSITION AND USE | Inspire Pharmaceuticals, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006104897-A2 | CYTOSKELETAL ACTIVE COMPOUNDS, COMPOSITION AND USE | INSPIRE PHARMACEUTICALS, INC. (US) | 2006-10-05 | — | — | WO | disclosed |
| US-20060217427-A1 | Cytoskeletal active compounds, compositions and use | INSPIRE PHARMACEUTICALS, INC. | 2006-09-28 | — | — | US | disclosed |