Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270520 | 1.00 | TLR7 (0.46) | TLR7TLR8ALDH1A1LMNA | |
| SCHEMBL25255842 | 0.86 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL25439213 | 0.85 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL25255753 | 0.84 | TLR7 (0.46) | TLR7TLR8 | |
| SCHEMBL31270543 | 0.84 | TLR7 (0.46) | TLR7TLR8 | |
| SCHEMBL25254083 | 0.83 | TLR7 (0.47) | TLR7TLR8 | |
| SCHEMBL25816890 | 0.82 | TLR7 (0.48) | TLR7TLR8 | |
| SCHEMBL25299191 | 0.78 | TLR7 (0.61) | TLR7TLR8 | |
| SCHEMBL31270951 | 0.76 | TLR7 (0.46) | TLR7TLR8LMNA | |
| SCHEMBL31025955 | 0.76 | TLR7 (0.41) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201933-A | Tri-fused ring compounds, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |