Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.63 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.63 |
| ▸ | RET | P07949 | 1/20 | 0.63 |
| ▸ | MET | P08581 | 1/20 | 0.63 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.63 |
| ▸ | TEC | P42680 | 1/20 | 0.63 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.63 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.63 |
| ▸ | BTK | Q06187 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.63 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25246476 | 0.94 | EGFR (0.66) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL25251987 | 0.90 | EGFR (0.69) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL30477149 | 0.90 | EGFR (0.69) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL25245223 | 0.90 | EGFR (0.72) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL30477188 | 0.90 | EGFR (0.66) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL25244182 | 0.90 | EGFR (0.66) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL25292539 | 0.89 | EGFR (0.67) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL25243591 | 0.89 | EGFR (0.64) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL25246957 | 0.88 | EGFR (0.66) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL3420728 | 0.87 | EGFR (0.81) | EGFRERBB2RIPK2RETMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023128350-A1 | HETEROARYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 비투에스바이오 | 2023-07-06 | — | — | WO | claimed |
| WO-2023128350-A1 | HETEROARYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 비투에스바이오 | 2023-07-06 | — | — | WO | disclosed |