Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.75 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 4/20 | 0.53 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27727395 | 1.00 | CA1 (0.75) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL27283295 | 1.00 | CA1 (0.75) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL28317258 | 1.00 | CA1 (0.75) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL16111913 | 1.00 | CA1 (0.75) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL4337688 | 1.00 | CA1 (0.75) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL12472571 | 0.96 | CA1 (0.69) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL11878966 | 0.96 | CA1 (0.69) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL9555043 | 0.96 | CA1 (0.69) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL437034 | 0.96 | CA1 (0.82) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL7316954 | 0.96 | CA1 (0.82) | CA1FFAR3LCKFYNCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3900932-B1 | METHOD FOR MANUFACTURING LAMINATED STEEL PLATE AND DEVICE FOR MANUFACTURING LAMINATED STEEL PLATE | THREE BOND CO LTD (JP) | 2024-03-06 | — | — | EP | disclosed |
| US-11872619-B2 | Method for manufacturing laminated steel sheet, apparatus for manufacturing laminated steel sheet, and curable composition used for the same | THREEBOND CO., LTD. (JP) | 2024-01-16 | — | — | US | disclosed |
| WO-2023130364-A1 | METHOD FOR TESTING VIRUS CONTENT OF WATER ON THE BASIS OF ALUMINUM SALT COAGULATION PRETREATMENT | 中国科学院生态环境研究中心 | 2023-07-13 | — | — | WO | disclosed |
| US-20220055088-A1 | METHOD FOR MANUFACTURING LAMINATED STEEL SHEET, APPARATUS FOR MANUFACTURING LAMINATED STEEL SHEET, AND CURABLE COMPOSITION USED FOR THE SAME | THREEBOND CO., LTD. (JP) | 2022-02-24 | — | — | US | disclosed |