SCHEMBL25255683

SCHEMBL25255683

CN1CCC=C(c2c[nH]c3c(CO)cccc23)C1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.57
ASH1L Q9NR48 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25298709 0.90 HTR2A (0.57) HTR2A
SCHEMBL25293251 0.88 HTR2A (0.55) HTR2A
SCHEMBL25255697 0.86 HTR2A (0.53) HTR2A
SCHEMBL25250221 0.86 HTR2A (0.60) HTR2A
SCHEMBL25242657 0.83 HTR2A (0.60) HTR2A
SCHEMBL25288178 0.82 HTR2A (0.66) HTR2A
SCHEMBL25769697 0.82 HTR2A (0.70) HTR2A
SCHEMBL25771290 0.82 HTR2A (0.59) HTR2A
SCHEMBL30548025 0.82 HTR2A (0.66) HTR2A
SCHEMBL25292468 0.81 HTR2A (0.58) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4447954-A1 HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS Icahn School of Medicine at Mount Sinai (US) 2024-10-23 EP disclosed
WO-2023114472-A1 HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2023-06-22 WO disclosed
WO-2023114472-A1 HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2023-06-22 WO disclosed