Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30481315 | 1.00 | PDE4B (0.48) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL25644847 | 0.94 | PIK3CD (0.50) | PDE4BPDE4DPDE4APDE4CIKBKB | |
| SCHEMBL30461672 | 0.94 | PIK3CD (0.50) | PDE4BPDE4DPDE4APDE4CIKBKB | |
| SCHEMBL25270113 | 0.94 | PIK3CD (0.50) | PDE4BPDE4DPDE4APDE4CIKBKB | |
| SCHEMBL29862920 | 0.85 | PIK3CD (0.54) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL23360628 | 0.85 | PIK3CD (0.54) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL2502944 | 0.82 | IKBKB (0.50) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL25422190 | 0.81 | USP30 (0.49) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL30481257 | 0.81 | USP30 (0.49) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL30481255 | 0.81 | USP30 (0.49) | PDE4BPDE4DPDE4APDE4CGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118843626-A | Heterocyclic compounds as DYRK1A inhibitors | 普罗塞纳生物科学有限公司 | 2024-10-25 | — | — | CN | disclosed |
| EP-4444421-A2 | HETEROCYCLIC COMPOUNDS AS DYRK1A INHIBITORS | Prothena Biosciences Limited (IE) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |