Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245340 | 1.00 | HRH3 (0.40) | HRH3AGXTQPCTLTA4HMAPT | |
| SCHEMBL30245435 | 0.94 | AGXT (0.43) | HRH3AGXTQPCTMAPTTSHR | |
| SCHEMBL30245109 | 0.94 | CETP (0.40) | HRH3QPCTLTA4HMAPTHTT | |
| SCHEMBL30244966 | 0.94 | HRH3 (0.40) | HRH3AGXTQPCTLTA4HMAPT | |
| SCHEMBL25251894 | 0.94 | CETP (0.40) | HRH3QPCTLTA4HMAPTHTT | |
| SCHEMBL25296186 | 0.94 | AGXT (0.43) | HRH3AGXTQPCTMAPTTSHR | |
| SCHEMBL25250353 | 0.94 | HRH3 (0.40) | HRH3AGXTQPCTLTA4HMAPT | |
| SCHEMBL25252797 | 0.94 | QPCT (0.43) | HRH3AGXTQPCTLTA4HMAPT | |
| SCHEMBL30245662 | 0.94 | QPCT (0.43) | HRH3AGXTQPCTLTA4HMAPT | |
| SCHEMBL30245183 | 0.92 | AGXT (0.42) | AGXTQPCTMAPTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |