⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL25300093 | 0.91 | LRRK2 (0.32) | — | |
| SCHEMBL25261130 | 0.90 | LRRK2 (0.36) | — | |
| SCHEMBL25840906 | 0.90 | LRRK2 (0.32) | — | |
| SCHEMBL25304577 | 0.89 | LRRK2 (0.36) | — | |
| SCHEMBL25259422 | 0.88 | LRRK2 (0.31) | — | |
| SCHEMBL26067423 | 0.88 | LRRK2 (0.31) | — | |
| SCHEMBL25261204 | 0.87 | LRRK2 (0.33) | — | |
| SCHEMBL25255188 | 0.84 | LRRK2 (0.32) | — | |
| Formic Acid SCHEMBL25304580 | 0.81 | LRRK2 (0.37) | — | |
| Formic Acid SCHEMBL25300942 | 0.81 | LRRK2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265109-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2023-08-24 | — | — | US | disclosed |
| WO-2023137166-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. (US) | 2023-07-20 | — | — | WO | disclosed |