Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270557 | 1.00 | TLR7 (0.47) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24539640 | 0.81 | TLR7 (0.55) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21550537 | 0.81 | PDE4A (0.42) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24539627 | 0.78 | TLR7 (0.68) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25296123 | 0.77 | TLR7 (0.48) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25294462 | 0.77 | TLR7 (0.36) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24539495 | 0.77 | TLR7 (0.51) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25258665 | 0.76 | TLR7 (0.52) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25301768 | 0.76 | TLR7 (0.46) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24539651 | 0.76 | TLR7 (0.50) | TLR7PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201933-A | Tri-fused ring compounds, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |