Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2533483 | 0.85 | — | — | |
| SCHEMBL19004774 | 0.83 | CA1 (0.52) | CA1FDPSCA2MAPK1ACE2 | |
| SCHEMBL3286382 | 0.83 | CA1 (0.52) | CA1FDPSCA2MAPK1ACE2 | |
| SCHEMBL2527272 | 0.82 | CA1 (0.47) | CA1FDPSCA2MAPK1ACE2 | |
| SCHEMBL10904102 | 0.81 | CA1 (0.50) | CA1FDPSMAPK1 | |
| SCHEMBL2526283 | 0.81 | CA1 (0.50) | CA1FDPSCA2MAPK1ACE2 | |
| SCHEMBL3099302 | 0.81 | CA1 (0.50) | CA1FDPSMAPK1 | |
| SCHEMBL15386609 | 0.81 | CA1 (0.50) | CA1FDPSCA2MAPK1ACE2 | |
| SCHEMBL2530545 | 0.80 | CA1 (0.45) | CA1FDPSMAPK1 | |
| SCHEMBL11245303 | 0.79 | CA1 (0.48) | CA1FDPSCA2MAPK1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |