Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 14/20 | 0.64 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.64 |
| ▸ | JAK2 | O60674 | 4/20 | 0.64 |
| ▸ | JAK1 | P23458 | 4/20 | 0.64 |
| ▸ | TYK2 | P29597 | 3/20 | 0.64 |
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
| ▸ | BTK | Q06187 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13074514 | 0.93 | JAK3 (0.66) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL12301740 | 0.89 | JAK3 (0.80) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL12301513 | 0.89 | JAK3 (0.63) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL2476310 | 0.88 | JAK3 (0.65) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL12321394 | 0.86 | JAK3 (0.60) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL12321922 | 0.86 | JAK3 (0.60) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL2480603 | 0.85 | JAK3 (0.59) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL12301515 | 0.85 | JAK3 (0.59) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL12301734 | 0.85 | JAK3 (0.64) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL2485607 | 0.84 | JAK3 (0.76) | JAK3IRAK4JAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023100918-A1 | NOVEL NICOTINAMIDE COMPOUND AND USE THEREFOR | 興和株式会社 | 2023-06-08 | — | — | WO | disclosed |
| WO-2023100918-A1 | NOVEL NICOTINAMIDE COMPOUND AND USE THEREFOR | 興和株式会社 | 2023-06-08 | — | — | WO | disclosed |