Adamantane

Adamantane

SCHEMBL25264306

C1C2CC3CC1CC(C2)C3.P

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.43
LMNA P02545 2/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
STAT6 P42226 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
SLC47A1 Q96FL8 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
POLB P06746 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adamantane SCHEMBL28761721 0.94 CYP2C9 (0.40) CYP2C9LMNASLC22A2SLC22A1GRIN2D
Adamantane SCHEMBL29707714 0.93 CYP2C9 (0.46) CYP2C9LMNASLC22A2SLC22A1GRIN2D
Adamantane SCHEMBL12761 0.93 CYP2C9 (0.46) CYP2C9LMNASLC22A2SLC22A1GRIN2D
Adamantane SCHEMBL1527414 0.93 CYP2C9 (0.46) CYP2C9LMNASLC22A2SLC22A1GRIN2D
Adamantane SCHEMBL9016497 0.93 CYP2C9 (0.46) CYP2C9LMNASLC22A2SLC22A1GRIN2D
Adamantane SCHEMBL21820021 0.86 CYP2C9 (0.43) CYP2C9LMNASLC22A2SLC22A1GRIN2D
Adamantane SCHEMBL20741994 0.86 CYP2C9 (0.43) CYP2C9LMNASLC22A2SLC22A1GRIN2D
Adamantane SCHEMBL21192802 0.86 CYP2C9 (0.43) CYP2C9LMNASLC22A2SLC22A1GRIN2D
Adamantane SCHEMBL21067465 0.86 CYP2C9 (0.43) CYP2C9LMNASLC22A2SLC22A1GRIN2D
Adamantane SCHEMBL6487737 0.86 CYP2C9 (0.43) CYP2C9LMNASLC22A2SLC22A1GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813528-A Synthesis method of all-carbon quaternary carbon cyclic ketone spiro indolenine derivative 江苏海洋大学 2023-09-29 CN claimed
EP-4180043-A1 RUTHENIUM COMPLEXES Universidad de Almeria (ES) 2023-05-17 EP claimed
EP-4180043-A1 RUTHENIUM COMPLEXES Universidad de Almeria (ES) 2023-05-17 EP disclosed
CN-111377934-B Heterocyclic compound, preparation and application thereof 中国科学院上海药物研究所 2023-01-24 CN disclosed
CN-103223350-A A catalyst system LUCITE INT UK LTD 2013-07-31 CN disclosed
CN-1681591-B Catalyst system LUCITE INT UK LTD 2012-04-18 CN disclosed
CN-1972750-A Catalyst system LUCITE INT UK LTD (GB) 2007-05-30 CN disclosed