Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 8/20 | 0.51 |
| ▸ | TACR2 | P21452 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL928992 | 0.80 | TACR3 (0.50) | TACR3GAATSHR | |
| SCHEMBL25280034 | 0.80 | TP53 (0.54) | TACR3TACR2KCNH2TP53 | |
| SCHEMBL31055679 | 0.80 | TP53 (0.54) | TACR3TACR2KCNH2TP53 | |
| SCHEMBL25225767 | 0.80 | TP53 (0.54) | TACR3TACR2KCNH2TP53 | |
| SCHEMBL928185 | 0.79 | TACR3 (0.57) | TACR3P2RX7GAATSHR | |
| SCHEMBL18417159 | 0.75 | TACR3 (0.48) | TACR3TSHRCREBBPNOTUM | |
| SCHEMBL18417158 | 0.75 | TACR3 (0.48) | TACR3TSHRCREBBPNOTUM | |
| SCHEMBL25219961 | 0.74 | TACR3 (0.47) | TACR3TACR2KCNH2TACR1 | |
| SCHEMBL25270063 | 0.74 | TACR3 (0.47) | TACR3TACR2KCNH2TACR1 | |
| SCHEMBL18916724 | 0.74 | TACR3 (0.56) | TACR3KCNH2GAATSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4190784-A1 | NITROGEN-CONTAINING FUSED RING DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2023-06-07 | — | — | EP | disclosed |