Cholestan-3Beta,5Alpha,6Beta-Triol

Cholestan-3Beta,5Alpha,6Beta-Triol

SCHEMBL25277367

CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CC(O)[C@@]4(O)CC(O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1L1 Q9UHC9 10/20 1.00
USP2 O75604 3/20 1.00
LMNA P02545 3/20 1.00
MEN1 O00255 1/20 1.00
TP53 P04637 1/20 1.00
KMT2A Q03164 1/20 1.00
NPC1 O15118 1/20 0.63
ABCB1 P08183 1/20 0.53
OSBP P22059 1/20 0.53
RORC P51449 1/20 0.53
OSBP2 Q969R2 1/20 0.53
CYP46A1 Q9Y6A2 1/20 0.53
NR1H3 Q13133 1/20 0.53
PLA2G1B P04054 1/20 0.53
POLA1 P09884 1/20 0.52
TOP2A P11388 1/20 0.52
TOP2B Q02880 1/20 0.52
CYP2D6 P10635 1/20 0.51
CYP2C19 P33261 1/20 0.51
NFKB1 P19838 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL29153013 1.00 NPC1L1 (1.00) NPC1L1USP2LMNAMEN1TP53
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL3421500 1.00 NPC1L1 (1.00) NPC1L1USP2LMNAMEN1TP53
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL14490136 1.00 NPC1L1 (1.00) NPC1L1USP2LMNAMEN1TP53
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL17049790 1.00 NPC1L1 (1.00) NPC1L1USP2LMNAMEN1TP53
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL15935528 1.00 NPC1L1 (1.00) NPC1L1USP2LMNAMEN1TP53
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL23647982 1.00 NPC1L1 (1.00) NPC1L1USP2LMNAMEN1TP53
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL18504407 1.00 NPC1L1 (1.00) NPC1L1USP2LMNAMEN1TP53
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL14360501 1.00 NPC1L1 (1.00) NPC1L1USP2LMNAMEN1TP53
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL21000300 1.00 NPC1L1 (1.00) NPC1L1USP2LMNAMEN1TP53
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL288840 1.00 NPC1L1 (1.00) NPC1L1USP2LMNAMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167231-A1 POLYESTER AND COATING MATERIAL INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-01 US claimed
US-20230167231-A1 POLYESTER AND COATING MATERIAL INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-01 US disclosed